Cephalosporins and Penicillins

Cephalosporins and Penicillins

Author: Edwin H. Flynn

Publisher: Elsevier

ISBN: 9781483270173

Category: Science

Page: 768

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Cephalosporins and Penicillins: Chemistry and Biology describes the studies made on cephalosporin in relation to the scientific and medicinal benefits that can be derived from cephalosporin C. This collection discusses how cephalosporin C is produced through modern isolation methods. One paper discusses its structure through chemical means, its degradation products, its derivative and other metabolic products such as penicillin N and cephalosporin P. Another paper explains the preparation method for 7-aminocephalosporanic acid and 6-aminopenicillanic acid through biological or chemical means. Another paper explains the alteration of the dihydrothiazine ring of the cephalosporins as the functionalities of these rings are chemically difficult to obtain. One paper also explains the rearrangements of cephalosporins and penicillins; cephalosporin can be synthesized from penicillin through an intermediacy of penicillin sulfoxide. Other papers discuss the pharmacology and toxicology of cephalosporins, as well as the practical tests and methods of assay that can be used in most cephalosporins, and in some cases, in penicillins. This book can prove useful for pharmacologists, microchemists, research workers, and technologists dealing with toxicology.
Cephalosporins and Penicillins
Language: en
Pages: 768
Authors: Edwin H. Flynn
Categories: Science
Type: BOOK - Published: 2013-10-22 - Publisher: Elsevier

Cephalosporins and Penicillins: Chemistry and Biology describes the studies made on cephalosporin in relation to the scientific and medicinal benefits that can be derived from cephalosporin C. This collection discusses how cephalosporin C is produced through modern isolation methods. One paper discusses its structure through chemical means, its degradation products,
Chemistry of Penicillin
Language: en
Pages: 1120
Authors: Hans T. Clarke
Categories: Medical
Type: BOOK - Published: 2015-12-08 - Publisher: Princeton University Press

This book makes available, for interested scientists to procure, absorb, and evaluate, the vast body of information on the research and results of the work on the chemistry of penicillin done in England and the United States during the war. The National Academy of Sciences arranged for the preparation of
Penicillins and Cephalosporins
Language: en
Pages: 594
Authors: Robert B. Morin, Marvin Gorman
Categories: Medical
Type: BOOK - Published: 2014-05-10 - Publisher: Academic Press

Chemistry and Biology of ?-Lactam Antibiotics, Volume 1: Penicillins and Cephalosporins provides information pertinent to the study of antibiotics containing the ?-lactam moiety. This book discusses the occurrence of a group of ?-lactam antibiotics structurally related to cephalosporin C. Organized into five chapters, this volume begins with an overview of
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It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of