Drug Safety in Clinical Practice

Drug Safety in Clinical Practice

Author: Peter I. Folb

Publisher: Springer Science & Business Media

ISBN: 9781447113515

Category: Medical

Page: 196

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Drugs may cause disease, or they may aggravate the morbidity of the condition for which they are prescribed, and certain patients may for one or other reason be particularly liable to drug injury. The inextricable relationships between the toxic profiles of drugs, the natural history of the diseases for which they are given, and the adverse drug effects that may develop in the course of such diseases are of considerable interest. It is the study of these rather neglected aspects of pharmacology and therapeutics which has formed the basis of this book. An explanation is required of the approach and the style which have been followed. The monograph does not purport to be comprehensive. Only important drug groups which are commonly used in practice are considered. Emphasis has been placed on achieving maximum benefit and safety of the appropriate drugs in the management of common illnesses. When treatment fails, either ab initio or subsequent to an initial response, the risk-benefit relationship of drugs inevitably alters. For this reason the main factors responsible for treatment failure have been considered, with special attention to the possible contribution of or implications for drug therapy in such a situation. Finally, proposals have been put forward for improving the diagnosis and reporting of adverse drug effects. In order to be practical and, as far as possible, constructive it has been necessary for me to "take a position" on numerous issues.
Drug Safety in Clinical Practice
Language: en
Pages: 196
Authors: Peter I. Folb
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

Drugs may cause disease, or they may aggravate the morbidity of the condition for which they are prescribed, and certain patients may for one or other reason be particularly liable to drug injury. The inextricable relationships between the toxic profiles of drugs, the natural history of the diseases for which
Statistical Methods for Evaluating Safety in Medical Product Development
Language: en
Pages: 400
Authors: A. Lawrence Gould
Categories: Health & Fitness
Type: BOOK - Published: 2015-02-23 - Publisher: John Wiley & Sons

This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during
Innovating for Patient Safety in Medicine
Language: en
Pages: 168
Authors: Rebecca Lawton, Gerry Armitage
Categories: Medical
Type: BOOK - Published: 2012-07-31 - Publisher: SAGE

This book helps the next generation of doctors understand how to contribute to making healthcare safer. Patient safety is increasingly important in medical practice today and is becoming a core part of training for medical students and foundation doctors. This book will enable the student or junior doctor to challenge
The Porphyrin Handbook: Medical aspects of porphyrins
Language: en
Pages: 347
Authors: Karl M. Kadish, Kevin M. Smith, Roger Guilard
Categories: Science
Type: BOOK - Published: 2000 - Publisher: Elsevier

The Porphyrin Handbook, Volume 14: Medical Aspects of Porphyrins provides information pertinent to every aspect of the chemistry, synthesis, spectroscopy, and structure of phthalocyanines. This book examines the biology and medical implications of porphyrin systems. Organized into 12 chapters, this volume begins with an overview of the underlying diagnostic features,
Patient Safety in Emergency Medicine
Language: en
Pages: 428
Authors: Pat Croskerry, Karen S. Cosby
Categories: Medical
Type: BOOK - Published: 2009 - Publisher: Lippincott Williams & Wilkins

With the increased emphasis on reducing medical errors in an emergency setting, this book will focus on patient safety within the emergency department, where preventable medical errors often occur. The book will provide both an overview of patient safety within health care—the 'culture of safety,' importance of teamwork, organizational change—and