Drug Safety in Clinical Practice

Drug Safety in Clinical Practice

Author: Peter I. Folb

Publisher: Springer Science & Business Media

ISBN: 9781447113515

Category: Medical

Page: 196

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Drugs may cause disease, or they may aggravate the morbidity of the condition for which they are prescribed, and certain patients may for one or other reason be particularly liable to drug injury. The inextricable relationships between the toxic profiles of drugs, the natural history of the diseases for which they are given, and the adverse drug effects that may develop in the course of such diseases are of considerable interest. It is the study of these rather neglected aspects of pharmacology and therapeutics which has formed the basis of this book. An explanation is required of the approach and the style which have been followed. The monograph does not purport to be comprehensive. Only important drug groups which are commonly used in practice are considered. Emphasis has been placed on achieving maximum benefit and safety of the appropriate drugs in the management of common illnesses. When treatment fails, either ab initio or subsequent to an initial response, the risk-benefit relationship of drugs inevitably alters. For this reason the main factors responsible for treatment failure have been considered, with special attention to the possible contribution of or implications for drug therapy in such a situation. Finally, proposals have been put forward for improving the diagnosis and reporting of adverse drug effects. In order to be practical and, as far as possible, constructive it has been necessary for me to "take a position" on numerous issues.
Drug Safety in Clinical Practice
Language: en
Pages: 196
Authors: Peter I. Folb
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

Drugs may cause disease, or they may aggravate the morbidity of the condition for which they are prescribed, and certain patients may for one or other reason be particularly liable to drug injury. The inextricable relationships between the toxic profiles of drugs, the natural history of the diseases for which
Promoting Safety of Medicines for Children
Language: en
Pages: 59
Authors: World Health Organization
Categories: Medical
Type: BOOK - Published: 2007 - Publisher: World Health Organization

Monitoring the safety of medicine use in children is of paramount importance since, during the clinical development of medicines, only limited data on this aspect are generated through clinical trials. Use of medicines outside the specifications described in the license (e.g. in terms of formulation, indications, contraindications or age) constitutes
Innovating for Patient Safety in Medicine
Language: en
Pages: 168
Authors: Rebecca Lawton, Gerry Armitage
Categories: Medical
Type: BOOK - Published: 2012-07-31 - Publisher: SAGE

This book helps the next generation of doctors understand how to contribute to making healthcare safer. Patient safety is increasingly important in medical practice today and is becoming a core part of training for medical students and foundation doctors. This book will enable the student or junior doctor to challenge
Software Innovations in Clinical Drug Development and Safety
Language: en
Pages: 303
Authors: Chakraborty, Partha
Categories: Medical
Type: BOOK - Published: 2015-10-02 - Publisher: IGI Global

In light of the rising cost of healthcare and the overall challenges associated with delivering quality care to patients across regions, scientists and pharmacists are exploring new initiatives in drug discovery and design. One such initiative is the adoption of information technology and software applications to improve healthcare and pharmaceutical
Drug Safety Data
Language: en
Pages: 312
Authors: Michael J. Klepper, Barton Cobert
Categories: Medical
Type: BOOK - Published: 2010-10-25 - Publisher: Jones & Bartlett Learning

Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk was selected for The First Clinical Research Bookshelf - Essential reading for clinical research professionals by the Journal of Clinical Research Best Practices. Drug Safety Data: How to Analyze, Summarize and Interpret to Determine Risk provides drug safety/pharmacovogilance