Free Fatty Acid Receptors

Free Fatty Acid Receptors

Author: Graeme Milligan

Publisher: Springer

ISBN: 9783319506937

Category: Medical

Page: 256

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This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands.
Free Fatty Acid Receptors
Language: en
Pages: 256
Authors: Graeme Milligan, Ikuo Kimura
Categories: Medical
Type: BOOK - Published: 2017-02-08 - Publisher: Springer

This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA
Obesity and Diabetes: Energy Regulation by Free Fatty Acid Receptors
Language: en
Pages:
Authors: Ikuo Kimura, Atsuhiko Ichimura
Categories: Medical
Type: BOOK - Published: 2016-02-03 - Publisher: Frontiers Media SA

Food intake regulates energy balance and its dysregulation leads to metabolic disorder, such as obesity and diabetes. During feeding, free fatty acids (FFAs) are not only essential nutrients but also act as signaling molecules in various cellular processes. Recently, several orphan G protein-coupled receptors (GPCRs) that act as FFA receptors
Role of Free Fatty Acid Receptors in the Regulation of Brain-derived Neurotrophic Factor Levels in the Enteric Glial and Endocrine Cells
Language: en
Pages:
Authors: Reem M. Alkahtani
Categories: Medical
Type: BOOK - Published: 2016 - Publisher:

Recent deorphanization of several G-protein-coupled receptors (GPRs) as endogenous receptors for free fatty acids (FFAs) has increased our understanding of these nutrients as signaling molecules and the integral role of gut microbiota in the regulation of host defense mechanisms, energy metabolism, gastrointestinal motility and secretion. There are five distinct FFA
Design and Synthesis of Ligands for Free Fatty Acid Receptors
Language: en
Pages: 186
Authors: Ole Buch Madsen Buch Madsen, Syddansk Universitet. Institut for Fysik, Kemi og Farmaci
Categories: Medical
Type: BOOK - Published: 2012 - Publisher:

Books about Design and Synthesis of Ligands for Free Fatty Acid Receptors
Characterization of the Effects of Free Fatty Acid Receptor 4 (FFA4) Agonists on Human Cancer Cells
Language: en
Pages:
Authors: Mandi Marie Hopkins
Categories: Cancer cells
Type: BOOK - Published: 2015 - Publisher:

The results of these studies establish that there are specific receptor(s) responsible for mediating the effects of omega-3 fatty acids on human cancer cells. This finding will facilitate the development of targeted pharmaceutical therapies for prevention and treatment of prostate and breast cancer. These results show for the first time