Free Fatty Acid Receptors
Author: Graeme Milligan
Publisher: Springer
ISBN: 9783319506937
Category: Medical
Page: 256
View: 406
Language: en
Pages: 256
Pages: 256
This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA
Language: en
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Food intake regulates energy balance and its dysregulation leads to metabolic disorder, such as obesity and diabetes. During feeding, free fatty acids (FFAs) are not only essential nutrients but also act as signaling molecules in various cellular processes. Recently, several orphan G protein-coupled receptors (GPCRs) that act as FFA receptors
Language: en
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Recent deorphanization of several G-protein-coupled receptors (GPRs) as endogenous receptors for free fatty acids (FFAs) has increased our understanding of these nutrients as signaling molecules and the integral role of gut microbiota in the regulation of host defense mechanisms, energy metabolism, gastrointestinal motility and secretion. There are five distinct FFA
Language: en
Pages: 186
Pages: 186
Books about Design and Synthesis of Ligands for Free Fatty Acid Receptors
Language: en
Pages:
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The results of these studies establish that there are specific receptor(s) responsible for mediating the effects of omega-3 fatty acids on human cancer cells. This finding will facilitate the development of targeted pharmaceutical therapies for prevention and treatment of prostate and breast cancer. These results show for the first time
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