Language: en
Pages: 256
Pages: 256
This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA
Language: en
Pages:
Pages:
Food intake regulates energy balance and its dysregulation leads to metabolic disorder, such as obesity and diabetes. During feeding, free fatty acids (FFAs) are not only essential nutrients but also act as signaling molecules in various cellular processes. Recently, several orphan G protein-coupled receptors (GPCRs) that act as FFA receptors
Language: en
Pages:
Pages:
Recent deorphanization of several G-protein-coupled receptors (GPRs) as endogenous receptors for free fatty acids (FFAs) has increased our understanding of these nutrients as signaling molecules and the integral role of gut microbiota in the regulation of host defense mechanisms, energy metabolism, gastrointestinal motility and secretion. There are five distinct FFA
Language: en
Pages:
Pages:
Books about Development of New Modulators of the Free Fatty Acid Receptors 1 and 2 (FFA1/GPR40 and FFA2/GPR43
Language: en
Pages: 184
Pages: 184
Books about Agonist-receptor Interactions Involved with Mobilization of Free Fatty Acids from Adipose Tissue