Microbial DNA and Host Immunity
Author: Eyal Raz
Publisher: Springer Science & Business Media
ISBN: 9781592593057
Category: Science
Page: 408
View: 229
Language: en
Pages: 408
Pages: 408
Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS , the process of cell activation, and the
Language: en
Pages: 428
Pages: 428
The immunostimulatory prospects of bacterial DNA have attracted the interest and attention of scientists and physicians and become a major focus in immunobiology and biomedicine. These activities are the product of immunostimulatory DNA sequences (ISS, also known as GpG motifs), which are rare in the mammalian genome. ISS were shown
Language: en
Pages: 368
Pages: 368
Microbial and host DNA are potent stimulators of innate immune responses and have been implicated in both host defense and autoimmune diseases. To date more than 10 immunological sensors of DNA have been proposed, and we are now beginning to understand the functions and mechanism of action of these proposed
Language: en
Pages:
Pages:
Trillions of commensal microbes reside on and inside the human body, including the intestinal and respiratory tracts, which encompass various microbial taxa, such as bacteria, fungi, archea and viruses. The close proximity of microbes with the host provides an opportunity to continually interact with each other. Advances in research approaches,
Language: en
Pages: 384
Pages: 384
Presents a comprehensive collection of DNA vaccine protocols. Divided into five sections, this volume contains state-of-the-art and practical procedures on the latest DNA vaccine technology, and demonstrates the tremendous progress that has been made in the field of DNA vaccination since the initial appearance of this new vaccination strategy.
