Microbial DNA and Host Immunity

Microbial DNA and Host Immunity

Author: Eyal Raz

Publisher: Springer Science & Business Media

ISBN: 9781592593057

Category: Science

Page: 408

View: 546

Download BOOK »

Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS , the process of cell activation, and the potential vaccination strategies using ISS. Specific pharmaceutical applications discussed include infectious disease (Hepatitis B, HIV, and mycobacterial infections), allergy (asthma and conjunctivitis), cancer (lymphoma), and inflammation and autoimmunity (arthritis and colitis).
Microbial DNA and Host Immunity
Language: un
Pages: 408
Authors: Eyal Raz
Categories: Science
Type: BOOK - Published: 2002-09-26 - Publisher: Springer Science & Business Media

Leading researchers review the activation of the mammalian immune system by bacterial DNA and its immunostimulatory sequences (ISS), and consider the applications of ISS in clinical medicine. The authors survey the latest findings concerning the receptor-recognition and signaling pathways triggered by ISS , the process of cell activation, and the
Microbial DNA and Host Immunity
Language: un
Pages: 428
Authors: Eyal Raz
Categories: Science
Type: BOOK - Published: 2002-09-26 - Publisher:

The immunostimulatory prospects of bacterial DNA have attracted the interest and attention of scientists and physicians and become a major focus in immunobiology and biomedicine. These activities are the product of immunostimulatory DNA sequences (ISS, also known as GpG motifs), which are rare in the mammalian genome. ISS were shown
Therapeutic Oligonucleotides
Language: en
Pages: 274
Authors: Yoon S. Cho-Chung, Alan M. Gewirtz, Cy A. Stein, National Institutes of Health (U.S.). Therapeutic Oligonucleotide Interest Group
Categories: Science
Type: BOOK - Published: 2003 - Publisher:

This work is concerned with various aspects of oligonucleotides including triplex DNA, transcription factor decoy, antisense DNA/RNA, ribozymes, PNA, 2',5'-oligoadenylates, RNAi, and CpG immune-stimulating oligomers, diagnostic oligonucleotide chips (DNA chips), and gene therapy vectors.
Dormancy and Low Growth States in Microbial Disease
Language: un
Pages:
Authors: Anthony R. M. Coates
Categories: Science
Type: BOOK - Published: 2003-06-02 - Publisher: Cambridge University Press

All cellular life-forms can exist in replicating and non-replicating states. Organisms replicate only when the conditions are beneficial, and when not replicating they concentrate on survival of these environmental stresses. Many bacteria, harmful to humans, survive the period of infection in a low growth state. This 2003 book addresses the
Biological DNA Sensor
Language: un
Pages: 368
Authors: Søren R. Paludan, Andrew G. Bowie
Categories: Medical
Type: BOOK - Published: 2013-10-30 - Publisher: Elsevier Inc. Chapters

Microbial and host DNA are potent stimulators of innate immune responses and have been implicated in both host defense and autoimmune diseases. To date more than 10 immunological sensors of DNA have been proposed, and we are now beginning to understand the functions and mechanism of action of these proposed